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成人HBV感染大多数是不显性感染,其一部分发生急性肝炎——一过性感染,目前在日本有300万人的HBsAg携带者——持续性染。作为携带者的发生机制,考虑有母儿间感染、父子间感染、来自同胞的感染、乳幼儿期的水平感染、免疫缺乏状态的感染等。针对携带者采取对策的关键是防止母儿间垂直感染。 1.HBV的母儿间垂直感染孕妇的携带率因人种、国别、地区及检出方法而异,不能一概而论,用RPHA法在千叶县检查的结果是1.5%(195/13,000),这些携带者所娩出婴儿1年后
Most adult HBV infections are insignificant infections, with a portion of acute hepatitis-transient infection and currently 3 million HBsAg carriers in Japan-persistent infections. As carriers of the mechanism of occurrence, consider the mother-child infection, father-son infection, from siblings, childhood infection, immunocompromised infection. The key to countermeasures for carriers is to prevent vertical infection between mother and child. 1. The carriage rate of pregnant women with vertical infection between mother and child in HBV varies according to ethnicity, country, region and detection method, and can not be generalized. The results of RPHA method in Chiba Prefecture were 1.5% (195 / 13,000) One year after the baby was delivered by these carriers