某些免疫病理情况,例如超敏反应和自身免疫疾病,是根据定量和/或定性免疫反应鉴定的。确信,免疫紊乱是由不当的内 部控制和调节所引起,而抗体本身是控制免疫反应的复杂调节网络的重要成员。 抗体是双分子,它的调节作用依赖于两条独立的分子结构,称为Fab和Fc部分。依靠Fab片段,抗体干扰抗原反应或参与基因型的交互作用。Fc片段介导的调节包括:影响补体激活、构成和清除免疫复合物、噬菌作用、ADCC活性,T-和B-细胞作用,细胞激素作用等。通常,抗体触发免疫反应,但也能抑制免 Certain immunopathological conditions, such as hypersensitivity and autoimmune diseases, are identified based on quantitative and / or qualitative immune responses. It is believed that immune disorders are caused by inappropriate internal control and regulation, and that the antibodies themselves are important members of a complex regulatory network that controls the immune response. An antibody is bimolecular and its regulation relies on two separate molecular structures, called the Fab and Fc parts. Depending on the Fab fragment, the antibody interferes with the antigen response or participates in the genotype interaction. Fc fragment-mediated regulation includes: complement activation, constitutive and clearance of immune complexes, phagocytosis, ADCC activity, T- and B-cell effects, cytokines and the like. Antibodies normally trigger an immune response, but they also inhibit immunity