手足口病(Hand-food-mouth disease,HFMD)是由多种肠道病毒引起的急性传染病,其中以CoxA、Ev71型感染多见,多发生于5岁以下儿童[1]。近10多年来,亚太地区发生过多起较大规模的流行,2008年4月,安徽阜阳出现多起儿童死亡病例,引起了中国卫生部的高度重视,并于同年5月2日把手足口 Hand-food-mouth disease (HFMD) is an acute infectious disease caused by various enteroviruses. Among them, CoxA and Ev71 infections are more common and occur mostly in children younger than 5 years of age [1]. In the past 10 years or so, there have been more large-scale epidemic in the Asia-Pacific region. In April 2008, there were many cases of child deaths in Fuyang, Anhui Province, causing great concern to the Chinese Ministry of Health. On May 2 of the same year,