胃食管反流病发生于老年病人(≥65岁),但关于治疗这类病人的抗分泌药效的资料甚少。根据有关处理规范,笔者对这类患者采取双盲安慰剂控制试验,收集资料。所有病人,开始时通过内诊镜检查确诊为进入性胃食管反流病(食管内pH检查)且有中度(糜烂)或重度(溃疡)食管炎,每日记录病情,6周和12周重复内镜检查。结果,治愈和症状的解除与这种病的年轻患者相似。对老年患者12周时的累加治愈率:安慰剂;38% Gastroesophageal reflux disease occurs in elderly patients (≥65 years of age), but little is known about the antisecretory efficacy of this class of patients. According to the relevant treatment specifications, the author of these patients double-blind placebo-controlled trials to collect data. All patients, initially diagnosed with invasive gastroesophageal reflux disease (esophageal pH examination) by endoscopy and had moderate (erosion) or severe (ulcerative) esophagitis, were documented daily for 6 weeks and 12 weeks Repeat the endoscopy. As a result, the cure and the resolution of symptoms are similar to those of young patients with the disease. Cumulative cure rates for elderly patients at 12 weeks: placebo; 38%