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应用流式细胞术（ＦＣＭ） 直接免疫荧光染色法和免疫粘附花环法， 检测了４１ 例慢性胃炎患儿外周血Ｔ 淋巴细胞亚群（ 包括ＣＤ３ ＋ ，ＣＤ４ ＋ 和ＣＤ８ ＋） 的变化和红细胞免疫功能（ＲＢＣＣ３ｂＲＲ，ＲＢＣＩＣＲ） ，以观察慢性胃炎患儿的免疫功能在治疗前后的变化。结果显示：慢性胃炎患儿治疗前各项免疫指标除ＲＢＣ－ ＩＣＲ 外，均低于对照组（ Ｐ＜ ０ ．０１） ；治疗后各项免疫指标均有显著提高，而ＲＢＣ－ ＩＣＲ 则有所下降（ Ｐ ＜ ０ ．０１） 。本研究提示，慢性胃炎患儿一旦确诊，就应及时正规治疗，以免患儿长期缺乏必需的营养素而致免疫功能紊乱。
The changes of T lymphocyte subsets (including CD3 +, CD4 + and CD8 +) in peripheral blood of 41 children with chronic gastritis were detected by flow cytometry (FCM) direct immunofluorescence staining and immunoadsorption rosette method. Immune function (RBC C3bRR, RBC ICR) to observe the changes of immune function in children with chronic gastritis before and after treatment. The results showed that all immunological indexes of children with chronic gastritis before treatment were lower than those of the control group except RBC-ICR (P <0.01); all the immune indexes were significantly increased after treatment, while RBC-ICR Decreased (P <0 .01). This study suggests that once the diagnosis of chronic gastritis in children, it should be timely and formal treatment, so as to avoid long-term lack of essential nutrients in children with immune dysfunction.