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瘦素是肥胖基因(ob基因)编码的蛋白产物,其最主要的功能是调节机体脂肪的沉积,同时其在生殖、造血系统、免疫应答和其他神经内分泌系统,如对肾上腺、甲状腺等均有一定作用。妇女妊娠期间体内的瘦素水平较之妊娠前有显著提高,并与胎儿的生长发育密切相关。近年发现,瘦素同妊娠期糖尿病的发病及其并发症,如巨大儿、胎儿生长受限、新生儿畸形等的发生均存在一定的相关关系,妊娠妇女瘦素水平的检测在妊娠期糖尿病的临床诊疗中也具有相当广泛的应用前景。
Leptin is a protein product encoded by the ob gene (ob gene). Its main function is to regulate the deposition of body fat, while its effects on reproduction, hematopoietic system, immune response and other neuroendocrine systems, such as on the adrenal gland and thyroid gland Certain effect. The level of leptin in pregnant women during pregnancy is significantly higher than that before pregnancy, and is closely related to the growth and development of the fetus. In recent years, found that leptin with gestational diabetes mellitus and its complications, such as macrosomia, fetal growth restriction, neonatal malformations, etc. there is a certain correlation between the detection of pregnant women, leptin levels in gestational diabetes Clinical diagnosis and treatment also has a very wide range of applications.