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口服甲氟哌啶25mg/kg,静脉注射甲氟哌啶15mg/kg,对恒速静脉注射哇巴因引起的豚鼠心律失常有对抗作用,口服甲氟哌啶50mg/kg能对抗氯化钙-乙酰胆碱引起的小鼠心律失常,并给缩短其心律失常持续时间,对抗此种心律失常的ED_(50)为5.64mg/kg,小鼠静脉注射甲氟哌啶的LD_(50)为35mg/kg。
Oral methylprednisolone 25mg / kg, intravenous injection of meclofen 15mg / kg, on constant intravenous injection of ouabain induced guinea pig arrhythmia antagonism, oral methylpiperidine 50mg / kg against calcium chloride - Acetylcholine caused arrhythmia in mice and shortened the duration of arrhythmia. The ED_ (50) against this arrhythmia was 5.64 mg / kg and the LD_ (50) of intravenous methylphenidate in mice was 35 mg / kg .