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目的 :评价紫杉醇联合顺铂对晚期乳腺癌的治疗作用。方法 :采用紫杉醇联合顺铂的联合方案 ,治疗晚期乳腺癌 78例 ,均为初治患者 ,均经细胞学或病理证实。结果 :本组完全缓解CR10 3% 8例 ,部分缓解PR5 3 8% 4 2例 ,(CR +PR)有效率 6 4 %。主要毒性为骨髓抑制及消化道反应。结论 :紫杉醇联合顺铂方案是治疗晚期乳腺癌较为理想的方案
Objective: To evaluate the therapeutic effect of paclitaxel plus cisplatin on advanced breast cancer. Methods: A total of 78 patients with advanced breast cancer were treated with paclitaxel combined with cisplatin. All of them were newly diagnosed patients, both of which were confirmed by cytology or pathology. Results: In this group, 8 cases of CR10 were completely relieved and 2 cases of PR5 38% were partially relieved. The effective rate of (CR + PR) was 64%. The main toxicity is myelosuppression and gastrointestinal reactions. Conclusion: Paclitaxel combined with cisplatin is an ideal treatment for advanced breast cancer