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进行性脑水肿常是重症脑炎的致死原因,积极处理至关重要。已有证明大剂量巴比妥能迅速降低由脑外伤所致的颅高压。也有少数报告本品对重症脑炎及脑膜炎有所俾益。作者报告6例急性重症脑炎以大剂量苯巴比妥联合传统脑水肿治疗的结果。6例急性脑炎依次并发于麻疹、水痘、传染性单核细胞增多症、流感、风疹及百日咳。原发病均经血清学证实,年龄自17个月～45岁。临床上多为深度昏迷及频繁阵挛性或强直性抽搐。脑电图均符合脑炎表现。
Progressive cerebral edema is often the cause of death of severe encephalitis, and active management is essential. It has been shown that high-dose barbiturates can rapidly reduce intracranial hypertension caused by traumatic brain injury. There are also a few reports of this product for the benefit of severe encephalitis and meningitis. The authors report the results of 6 cases of acute severe encephalitis treated with high-dose phenobarbital combined with traditional cerebral edema. Six cases of acute encephalitis were followed by measles, chickenpox, infectious mononucleosis, flu, rubella and whooping cough. Primary disease were confirmed by serology, age from 17 months to 45 years old. Clinically, mostly deep coma and frequent clonic or tonic twitch. EEG are in line with encephalitis performance.