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目的调查与分析本院呼吸内科住院患者抗菌药物的使用情况,对其合理性进行比较和评价,促进临床合理用药。方法随机抽取本院呼吸内科2013-01~12期间出院病历360份,以Excel表格对抗菌药物的使用例数、使用种类、药敏试验、联合用药等进行分类统计结果。结果本院呼吸内科住院患者抗菌药物的使用率为93.6%,使用强度为42.5(DDD/100人天);以静脉滴注(98.2%)和单用抗菌药(55.8%)为主;从用药频度看,以第三代头孢菌素(31.1%)、氟喹诺酮类(26.9%)和青霉素类(25.6%)为主。联合用药率为44.2%,病原学送检率为91.1%,发生药物不良反应5例,发生率1.4%。结论本院呼吸内科抗菌药物使用基本合理,但也有个别盲目联用抗菌药及盲目更换抗菌药或使用疗程不合理等现象,应进一步提高合理用药水平。
Objective To investigate and analyze the use of antibacterials in inpatients of respiratory medicine in our hospital and to compare and evaluate their rationality to promote rational drug use in clinic. Methods We randomly selected 360 medical records of discharge from 2013-01 to 2012 in our hospital, and classified the use of antibacterials, types of use, drug susceptibility test and combination therapy in Excel format. Results The inpatient use of antibiotics in our hospital was 93.6% with a strength of 42.5 (DDD / 100 days), intravenous drip (98.2%) and single antibacterial drug (55.8%), Frequency, with the third generation cephalosporins (31.1%), fluoroquinolones (26.9%) and penicillins (25.6%) based. The combination rate was 44.2%, the rate of etiological examination was 91.1%, and adverse drug reactions occurred in 5 cases, the incidence rate was 1.4%. Conclusion The use of antibacterials for respiratory medicine in our hospital is basically reasonable, but there are also some blindly combined antibacterials and the blind replacement of antibacterials or the use of unreasonable treatment, which should be further improved.