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飞秒激光以其独特的优势广泛应用于角膜屈光手术。角膜屈光手术通过切削角膜来改变屈光状态的同时也改变了角膜的组织结构及其生物力学特性,不同的手术方式对角膜生物力学的改变也有所不同。目前临床上常用的飞秒激光角膜屈光手术有飞秒激光辅助的角膜原位磨镶术(FS-LASIK)和飞秒激光小切口角膜基质透镜取出术(SMILE)。本文就角膜生物力学特性的结构基础,目前常用的角膜生物力学测量方法,FS-LASIK手术中瓣厚度、侧切角度、残余基质床厚度、瓣蒂方向等参数的设置,及SMILE手术中切口大小、光学区大小、帽厚度、组织切削量等参数的设置对角膜生物力学的影响进行综述。“,”Femtosecond laser has been widely used in corneal refractive surgery.The refractive state, corneal tissue structure and biomechanical properties are changed through cutting the corneal tissue.Femtosecond laser-assisted in situ keratomileusis(FS-LASIK)and small incision lenticule extraction(SMILE)are the most commonly used femtosecond laser corneal refractive surgery.In this study, the structural basis of corneal biomechanical properties, the commonly used methods for corneal biomechanics measuring, biomechanical effect of corneal flap thickness, side-cut angles, residual stromal bed thickness, flap hinge position for F-LASIK and the size of corneal incision, optical zone diameter, cap thickness, tissue cutting thickness for SMILE on corneal biomechanics are reviewed.