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作者报道1例28岁妇女,有癫痫史14年,服抗癫痫药可控制发作,曾正常分娩3胎,过去无输血史。在第4次妊娠的14周出现直接抗人球蛋白试验阳性,6周后即孕23周发现贫血,经铁剂及叶酸治疗,贫血反而加重,病人因发热、咽痛5天入院。入院时呈全血细胞减少,伴鼻衄、皮肤紫癜和采血处血肿;Hb 7.73/dl,WBC 2600/μl,血小板 7000/μl;GPF正常,无黄疸。经检测证实红细胞表面有IgG及补体;血小板膜抗糖蛋白Ⅱb/ⅢA抗体阳性。经
The authors report a 28-year-old woman with a 14-year history of epilepsy who was able to control the onset of antiepileptic drugs. She had a normal childbirth of 3 and had no previous history of blood transfusions. 14 weeks in the fourth pregnancy, a direct anti-human globulin test positive, 6 weeks after 23 weeks of pregnancy that anemia, iron and folic acid treatment, anemia but aggravated, the patient was fever, sore throat 5 days admission. Complete pancytopenia on admission, accompanied by epistaxis, skin purpura and blood collection hematoma; Hb 7.73 / dl, WBC 2600 / μl, platelet 7000 / μl; GPF normal, no jaundice. The test showed that erythrocyte surface IgG and complement; platelet anti-glycoprotein Ⅱ b / Ⅲ A antibody positive. through