论文部分内容阅读
原发性胆汁性肝硬化(PBC)的男性发病率远低于女性,文献中未见对男性患者临床生化及病理组织学表现估价的报告。本文分析有组织学诊断且抗线粒体抗体阳性的30例男性患者,其中5例无肝胆病症状,2例无胆汁郁积的生化及组织学证据。另以30例年龄相仿的女性患者作为对照,旨在确定两性之间有无差别。PBC的诊断标准为病理组织学所见有下列特点中两项以上,1.慢性非化脓性破坏性胆管炎,2.肝小叶间胆管减少,3.慢性胆汁潴留证据,包括下列各点中两点以上:
The prevalence of males in primary biliary cirrhosis (PBC) is much lower than that in females, and no reports of clinical biochemical and histopathological findings in men have been reported in the literature. In this paper, 30 male patients diagnosed histologically and resistant to anti-mitochondrial antibodies were analyzed, of whom 5 had no symptoms of hepatobiliary disease and 2 had no biochemical and histological evidence of cholestasis. Another 30 cases of similar age female patients as a control, to determine whether there is any difference between the sexes. The diagnostic criteria for PBC are two or more of the following characteristics seen in histopathology, 1. Chronic non-suppurative destructive cholangitis, 2. Interhepatic interlobular bile duct reduction, 3. Evidence of chronic bile retention, including the following two points Point above: