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膜增殖性肾炎(MPGN)患者的乙型肝炎病毒(HBV)携带率明显高于其他肾炎患者和普通人群。为了探讨HBV感染与MPGN的关系,我们对84例MPGN成人患者进行了临床,病理与免疫病理研究。材料和方法 84例均为1984年7月～1992年2月间经肾穿刺活检诊断为MPGN的患者,男性60例,女性24例,平均年龄31.3±11.4岁。血清学检查包括HBV-DNA(斑点杂交、北京医科大学肝病研究所提供HBV-DNA探针)、
Hepatitis B virus (HBV) carrier rates in patients with proliferative glomerulonephritis (MPGN) are significantly higher than those in other nephritis patients and the general population. To investigate the relationship between HBV infection and MPGN, 84 adult MPGN patients were studied clinically, pathologically and immunopathologically. Materials and Methods 84 cases were diagnosed as MPGN by renal biopsy between July 1984 and February 1992. There were 60 males and 24 females with an average age of 31.3 ± 11.4 years. Serological tests include HBV-DNA (dot blot, Beijing Medical University Institute of Hepatology provide HBV-DNA probe),