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有安慰剂对照的研究发现,米索前列醇(misoprostol)能明显降低接受非甾体抗炎药(NSAID)治疗的关节炎病人胃溃疡和十二指肠溃疡的发生率,经纤维内窥镜检查,证实胃和十二指肠溃疡分别减少了75%和87%。米索前列醇分别对组胺H2受体阻滞剂雷尼替丁或硫糖铝的比较研
A placebo-controlled study found that misoprostol significantly reduced the incidence of gastric ulcer and duodenal ulcer in arthritis patients treated with non-steroidal anti-inflammatory drugs (NSAIDs) Check, confirmed stomach and duodenal ulcer decreased by 75% and 87%. Comparative study of misoprostol on ranitidine or sucralfate, a histamine H2 receptor blocker