论文部分内容阅读
1976年4月至1986年4月间对 Ib 以上287例宫颈癌根治手术病人进行术后二年内给以维持化疗治疗,对照组286例。两组均不包括术后六个月内复发的病人。化疗组5年及10年生存率分别为95％及90％;对照组分别为86％及82％。化疗组第一年的危险率是1％、第二年以后降至0. 1以下。从两组病情进展者的生存率曲线看两组间差别很大。进一步说明维持化疗有效。无淋巴结转移的两组生存率均高,危险率5％差异明显。有淋巴结转移的、维持化疗组10年生存率为80％;而对照组仅55％。说明化疗对淋巴结转移复发的高危组也有明显疗效。
From April 1976 to April 1986, 287 patients with radical resection of cervical cancer who had undergone Ib operation were treated with chemotherapy for two years after operation, and 286 patients in the control group. Neither group included patients who relapsed within six months after surgery. The 5-year and 10-year survival rates were 95% and 90% in the chemotherapy group and 86% and 82% in the control group, respectively. The risk of chemotherapy in the first year is 1%, after the second year fell below 0.1. From two groups of disease progression rate of survival curves to see the two groups vary widely. Further instructions to maintain chemotherapy effective. No survival rate of the two groups of lymph node metastasis were high, the risk of 5% significant difference. With lymph node metastasis, the 10-year survival rate was 80% in the maintenance chemotherapy group compared to 55% in the control group. Chemotherapy on lymph node metastasis recurrence of high-risk group also had a significant effect.