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目的探讨根管治疗中不同冲洗消毒药物对牙周牙髓联合病变的疗效。方法选取东莞市南城医院2016年8月至2017年8月收治的40例牙周牙髓联合病变患者作为研究对象,根据患者就诊时间随机分为研究组和对照组,每组20例。研究组患者给予替硝唑溶液冲洗联合盐酸米诺环素消毒,对照组患者给予次氯酸钠溶液冲洗联合氢氧化钙和洗必泰混合封消毒,观察两组患者治疗前后临床牙周指标以及治疗效果。结果治疗6周后,研究组PLI、BI、PD、CAL均优于对照组,组间比较差异均有统计学意义(均P<0.05);治疗12周后,研究组患者CAL明显低于对照组,差异有统计学意义(P<0.05),两组患者PD、PLI、BI比较差异均无统计学意义(均P>0.05);研究组患者总治疗有效率为95.0%,优于对照组的55.0%,组间比较差异有统计学意义(P<0.05)。结论替硝唑溶液超声荡洗联合盐酸米诺玛素消毒可改善牙周牙髓联合病变患者牙周临床指标,提高临床治疗效果。
Objective To investigate the curative effect of different irrigation and disinfecting drugs on periodontal and pulp combined diseases in root canal therapy. Methods Forty cases of periodontal-pulp-joint disease patients from August 2016 to August 2017 in Nancheng Hospital of Dongguan City were selected as study subjects. They were randomly divided into study group and control group, with 20 cases in each group. Patients in the study group were treated with tinidazole solution flushing combined with minocycline hydrochloride disinfection, while patients in the control group were given sodium hypochlorite solution flushing combined with calcium hydroxide and chlorhexidine mixed seal disinfection. Clinical periodontal indexes and therapeutic effects were observed before and after treatment in both groups. Results After 6 weeks of treatment, the PLI, BI, PD, CAL in the study group were better than those in the control group, with significant differences between the two groups (all P <0.05); after 12 weeks of treatment, the CAL in the study group was significantly lower than that in the control group (P <0.05). There was no significant difference in PD, PLI and BI between the two groups (all P> 0.05). The total effective rate of the study group was 95.0%, which was better than that of the control group 55.0%, there was significant difference between the two groups (P <0.05). Conclusion Tinidazole solution ultrasonic washing combined with minocycline disinfection can improve the periodontal clinical indicators of patients with periodontal and pulp joint disease and improve the clinical effect.