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我科于1985年开始用本法治疗外阴白色病变90例,同时观察局部临床及病理组织学改变,证明近期疗效显著。本组病人症状及局部改变、病理组织学改变均符合本症。其中增生型营养不良54例(5例轻度不典型增生);混合型营养不良18例(1例轻度不典型增生);硬化苔癣型18例。目前认为重度不典型增生属癌前病变。另有研究表明本症局部上皮代谢较正常增加3～6倍。用~(32)P 吸收实验表明本症与原位癌吸收量相等,此点为我们用本法治疗外阴白色病变提供了依据。还有研究发现本症局部组织中抑素及刺激物失调而引起临床及病理改变,据此我们用抗代谢药物试图进
Our department began in 1985 with the treatment of 90 cases of white lesions of the vulva, while observing local clinical and histopathological changes to prove the recent significant effect. The symptoms and local changes in patients with histopathological changes are in line with this disease. There were 54 cases of hyperplastic malnutrition (5 cases of mild dysplasia), 18 cases of mixed malnutrition (1 case of mild dysplasia) and 18 cases of lichen sclerosus. Currently considered severe atypical hyperplasia is precancerous lesions. Another study shows that the local epithelial metabolism of the normal increase of 3 to 6 times. ~ (32) P absorption experiments showed that the disease and in situ cancer absorption equal to this point for the treatment of vulvar white lesions with this method provides the basis. There are also studies found that the local tissue in the somatostatin and stimuli imbalance caused by clinical and pathological changes, therefore we try to use anti-metabolic drugs into