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报道７例患重症肺疾病新生儿，平均出生体重１１７２±８２８ｇ，孕周３１±４．２周，表现为肺动态顺应性差（０．０２±０．０１２ｍｌ、ｋｐａ~（－１）．ｋｇ~（－１）），虽用高氧（０．８８±０．１３），高平均气道压（１．１４±０．１３ｋｐａ）机械通气治疗仍不能维持正常血气或出现严重肺间质气肿，经改用高频振荡、高肺容量策略通气后、氧合在４小时内均改善、高碳酸血症在１２小时内得以纠正。７例中６例撤离成功，共存活４例，１例并发Ⅰ～Ⅲ度室管膜下－脑室内出血。表明新生儿重症肺疾病，经传统机械通气（ＣＭＶ）治疗失败时，改用高频振荡通气可改善气体交换，提示高频振荡通气可作为一种抢救重症新生儿呼吸衰竭新的有效手段。
Seven newborns with severe pulmonary disease were reported, with an average birth weight of 1172 ± 828g and a gestational age of 31 ± 4.2 weeks, showing poor pulmonary dynamic compliance (0.02 ± 0.012ml, kpa ~ (-1) (-1)). Although high-oxygen (0.88 ± 0.13) and high mean airway pressure (1.14 ± 0.13kpa) mechanical ventilation could not maintain normal blood gas or severe pulmonary interstitial emphysema , The use of high-frequency oscillation, high lung ventilation strategy ventilation, oxygenation in 4 hours were improved, hypercapnia in 12 hours to be corrected. Of the 7 cases, 6 cases were evacuated successfully, 4 cases survived, and 1 case had subependymeal-ventricular hemorrhage Ⅰ ~ Ⅲ degree. Show neonatal severe lung disease, the failure of traditional mechanical ventilation (CMV) treatment, the use of high-frequency oscillatory ventilation can improve gas exchange, suggesting that high-frequency oscillatory ventilation can be used as a rescue of severe neonatal respiratory failure a new effective means.