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利福平(RFP)1967年开始用作抗结核治疗,Poole等首先报告其不良反应,尔后,国内屡有报道。但绝大多数为急性不良反应,至于引起慢性不良反应较为少见。我院见一例持续服利福平近7个月,引起慢性肝肾损害达2年10个月,现报道于下。男,50岁,干部。因摄胸片诊断两上肺浸润型肺结核,进展期,痰菌(一),于1982年5月23日开始用利福平600mg、乙胺丁醇750mg、异菸肼300mg,每日分3次服,无不良反应。服药至同年12月20日,
Rifampicin (RFP) started its anti-TB treatment in 1967 and Poole et al. First reported its adverse reactions. Subsequently, it was reported frequently in China. However, the vast majority of acute adverse reactions, as the cause of chronic adverse reactions are less common. See a case in our hospital continued to take rifampicin for nearly 7 months, causing chronic liver and kidney damage up to 2 years and 10 months, are reported below. Male, 50 years old, cadre. Diagnosed on both sides of the chest X-ray pulmonary infiltrative pulmonary tuberculosis, advanced, sputum bacteria (a), May 23, 1982 began with rifampicin 600mg, ethambutol 750mg, isoniazid 300mg, day 3 Second service, no adverse reactions. Take medicine to the same year on December 20,