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对1992年起在中国西南边境瑞丽等县建立的吸毒人群HIV感染率及发病率观察的现场,每年进行追踪调查,1992～1995年历年各调查859、437、343及540名,共2 179名。3县吸毒人群中静注者比例约为30%。1995年上升至近50%。瑞丽县静注毒品者HIV感染率较高,1992～1995年历年为81.8%、85.7%、61.8%及51.9%;陇川县居中。历年为44.6%、40.0%、42.4%及43.5%;潞西县一直维持较低水平,历年为5.1%、0%、0%及3.1%。1992～1995年瑞丽静注毒品者中HIV抗体阴性者的发病率(每百人年)较高,为21.7%～42.1%,平均30.1%;陇川次之,为12.1%～25.9%,平均17.2%;潞西较低,为0%～2.3%,平均为0.6%。3县HIV感染者的配偶的感染率1990年为3.1%,1992～1995年为9.8%、7.4%、0%及10.3%,1997年为12.3%。对107名HIV感染者CD_4细胞测定表明,感染年份越早,CD_4细胞计数<500/mm~3者所占的比例越高。对29名用NASBA法测定病毒载量(Viral load)。其中3名<1 000拷贝/ml,其余26名的病毒载量对数(10g)平均值为4.37。
A follow-up survey was conducted each year on the site of HIV infection rate and incidence observed among drug users popularized in Ruili and other counties in southwestern China since 1992. A total of 2 179 individuals, 859, 437, 343 and 540 were investigated from 1992 to 1995 . 3 county drug users intravenous injection ratio of about 30%. In 1995 it rose to nearly 50%. The rate of HIV infection among intravenous drug users in Ruili County was high, accounting for 81.8%, 85.7%, 61.8% and 51.9% respectively from 1992 to 1995, and Longchuan County was the middle one. Over the years, they were 44.6%, 40.0%, 42.4% and 43.5% respectively. Luxi County remained at a relatively low level of 5.1%, 0%, 0% and 3.1% over the years. From 1992 to 1995, the incidence of HIV antibody-negative persons in Ruili intravenous drug abusers was high (from 100 to 100 years), ranging from 21.7% to 42.1% with an average of 30.1%; followed by Longchuan from 12.1% to 25.9% with an average of 17.2 %; Luxi low, 0% to 2.3%, with an average of 0.6%. In 3 counties HIV-infected spouses were 3.1% infected in 1990, 9.8%, 7.4%, 0% and 10.3% in 1992-1995 and 12.3% in 1997. The determination of CD_4 cells in 107 HIV-infected patients showed that the earlier the infection year, the higher the proportion of CD_4 cells count <500 / mm ~ 3. Of 29 patients, the viral load was determined by the NASBA method. Three of them were <1 000 copies / ml, and the average of the other 26 viral load logs (10 g) was 4.37.