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类风湿关节炎(RA)是一自身免疫病,关节腔内滑膜液免疫球蛋白G类风湿因子(IgG RF)在本病发病及鉴别诊断中均有一定意义。本文采用ELISA间接法检测了35例风湿性疾病(其中RA12例)膝关节滑膜液中的IgG RF,并进行了总结、分析。材料与方法一、病例的选择 35例各种风湿病患者滑膜液标本取自北京协和医院内科及北京建筑工人医院骨科门诊及住院患者,部分是为诊断和治疗目的而抽取的膝关节滑膜液,其余大部分均为施行膝关节镜手术者的膝关节滑膜液,其中RA 12例,男性3例、女性9例,年龄17～57岁;病程最长者20年,最短者1年,平均9年。此外,反应性关节炎(ReA)7例、骨性关节炎(OA)5例,各种非滑膜炎患者(Non-
Rheumatoid arthritis (RA) is an autoimmune disease. The intra-articular synovial fluid immunoglobulin G-like rheumatoid factor (IgG RF) has a certain significance in the pathogenesis and differential diagnosis of this disease. In this paper, IgG indirect immunosorbent assay (ELISA) was used to detect IgG RF in synovial fluid of 35 rheumatic diseases (including RA12 cases), and the results were summarized and analyzed. Materials and methods First, the choice of cases 35 cases of rheumatoid synovial fluid specimens from patients with Peking Union Medical College Hospital and Beijing Construction Workers Hospital orthopedic outpatient and inpatient, in part for the diagnosis and treatment purposes, the extraction of the knee synovium Liquid, most of the rest are knee synovial fluid of patients undergoing knee arthroscopy surgery, including 12 cases of RA, 3 males and 9 females, aged 17 to 57 years; the longest course of 20 years, the shortest of 1 year , An average of 9 years. In addition, 7 cases of reactive arthritis (ReA), 5 cases of osteoarthritis (OA), a variety of non-synovitis patients (Non-