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[目的]探讨血必净联合辅助呼吸对急性肺损伤(ALI)/急性呼吸窘迫综合征(ARDS)病人的治疗作用。[方法]选择40例急性肺损伤(ALI)/急性呼吸窘迫综合征患者随机分为对照组和实验组,每组各20例。对照组采取辅助呼吸、抗炎治疗、对症和常规补液;实验组在对照组治疗的基础上给予滴注血必净50ml,2次/d,共注射7d。对两组患者的用药及治疗7d后比较疗效,指标包括:血液中白细胞、C-反应蛋白、气道压力、血气分析和脱机的百分比,以及重症监护病房的死亡率。[结果]治疗前两组患者各项指标比较差异无统计学意义(P﹥0.05);应用改善措施7d,实验者患者各项评价指标与对照组比较差异均有统计学意义(P﹤0.05),最终的脱机率实验组明显优于对照组(P﹤0.05),实验者罹患该病患者的死亡率明显低于对照组(P﹤0.05)。[结论]血必净联合辅助呼吸可以显著提高罹患急性肺损伤(ALI)和急性呼吸窘迫综合征(ARDS)患者的脱机率,患者的死亡率显著减低,值得临床广泛推广应用。
[Objective] To investigate the therapeutic effect of Xuebijing combined with assisted breathing on patients with acute lung injury (ALI) / acute respiratory distress syndrome (ARDS). [Methods] Forty patients with acute lung injury (ALI) / acute respiratory distress syndrome were randomly divided into control group and experimental group, with 20 cases in each group. The control group was assisted breathing, anti-inflammatory treatment, symptomatic and routine rehydration; experimental group in the control group on the basis of the treatment given dripping Xuebijing 50ml, 2 times / d, a total of 7d. The efficacy of the two groups of patients after treatment and treatment of 7d, the indicators include: white blood cells in the blood, C-reactive protein, airway pressure, blood gas analysis and the percentage of off-line, and mortality in the intensive care unit. [Results] There was no significant difference in each index between the two groups before treatment (P> 0.05). After the improvement measures were applied for 7 days, there were significant differences between the experimental subjects and the control group (P <0.05) , And the final off-rate was significantly better in the experimental group than in the control group (P <0.05). The mortality rate of the experimental subjects with the disease was significantly lower than that of the control group (P <0.05). [Conclusion] Xuebijing combined with assisted breathing can significantly improve the off-rate of patients with acute lung injury (ALI) and acute respiratory distress syndrome (ARDS), the mortality rate of patients is significantly reduced, which is worthy of wide application in clinic.