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目的:探讨全血细胞减少在13种恶性血液病中所占的比例及发生率。方法:回顾655例初诊恶性血液病患者的外周血细胞检测结果,分析全血细胞减少患者在13种恶性血液病中所占比例及发生率。结果:655例患者中共有81例出现全血细胞减少,在13种恶性血液病中所占的比例由多到少依次为M4/M5、ALL、NHL、MF、M2、M7、M6、M1、MM、CML、HCL、M0、M3;髓系中M0、MF、M1、M7、M6、M4/M5、CML、M2和M3的发生率分别为75.0%、56.0%、50.0%、45.0%、33.0%、13.0%、9.0%、5.0%和3.0%,淋系中HCL、MM、NHL和ALL的发生率分别为50.0%、50.0%、36.0%和6.0%。结论:恶性血液病出现全血细胞减少与各类型疾病的临床发病率和各自病理特点有关。
Objective: To investigate the percentage and incidence of pancytopenia in 13 hematologic malignancies. Methods: The peripheral blood cells of 655 newly diagnosed patients with hematologic malignancies were retrospectively analyzed. The proportion and incidence of pancytopenia in 13 hematologic malignancies were analyzed. RESULTS: A total of 81 patients with pancytopenia were found in 655 patients, with the proportion of M4 / M5, ALL, NHL, MF, M2, M7, M6, M1, MM CML, HCL, M0 and M3 in the myeloid line were 75.0%, 56.0%, 50.0%, 45.0% and 33.0% , 13.0%, 9.0%, 5.0% and 3.0% respectively. The incidences of HCL, MM, NHL and ALL in the lymph nodes were 50.0%, 50.0%, 36.0% and 6.0%, respectively. Conclusion: The incidence of pancytopenia in hematologic malignancies is related to the clinical morbidity and pathological features of various types of diseases.