论文部分内容阅读
目的分析山东省淄博市2014年-2016年手足口病病原体检测数据,掌握本市手足口病流行趋势,为制定预防控制措施提供科学依据。方法采用实时荧光逆转录PCR(RT-PCR)方法对分布在9个区县的1 648份样品进行分型检测,用SPSS 16.0软件对数据进行统计分析。结果 1 648份咽拭子标本的病毒核酸阳性率为71.72%。不同性别、不同年度和不同年龄样品的检测结果分布差异均有统计学意义(χ~2值分别为9.35、524.32、37.60,P<0.05);临淄区的患者阳性率最高(80.93%),而沂源县的阳性率最低(37.66%);本市手足口阳性样本在时间分布上从3月份开始逐步增加,到6月达到顶峰,之后逐月下降,5月-8月为高发月份。结论 2014年-2016年山东省淄博市肠道病毒优势病原体交替流行,无固定型别。1岁~3岁年龄组是手足口病的重点防护人群,每年3月份之后应重点加强手足口病疫情监测及防控,对重点地区进行手足口病卫生知识宣传教育及防控工作。
Objective To analyze the pathogen detection data of hand-foot-mouth disease from 2014 to 2016 in Zibo City, Shandong Province, to grasp the epidemic trend of hand-foot-mouth disease in this city and to provide a scientific basis for making prevention and control measures. Methods 1 648 samples distributed in 9 districts and counties were detected by real-time fluorescence reverse transcription PCR (RT-PCR). The data were analyzed by SPSS 16.0 software. Results The positive rate of viral nucleic acid in 1 648 throat swab specimens was 71.72%. The distribution of test results in different sex, different years and different ages were statistically significant (χ ~ 2 values were 9.35,524.32,37.60, P <0.05), while the highest positive rate was found in Linzi District (80.93%) The positive rate of Yiyuan County was the lowest (37.66%); the positive samples of hand, foot and mouth in this city increased gradually from March to June and peaked in June, then decreased month by month, and May-August was the high-incidence month. Conclusion From 2014 to 2016, predominant pathogens of enterovirus in Zibo City, Shandong Province were alternately epidemic with no fixed type. The 1-year-old to 3-year-old group is the key protective population of hand-foot-mouth disease. After March each year, the monitoring and prevention and control of hand-foot-mouth disease epidemic should be strengthened and publicity, education and prevention of hand-foot-mouth disease health knowledge should be carried out in key areas.