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目的:利用液基薄层细胞技术(TCT)对12 672例宫颈标本进行细胞学检测,探讨宫颈癌的发病情况及TCT在妇科疾病诊断中的意义。方法:2006年2月～2008年2月进行宫颈细胞学检测的12 672例宫颈标本采用液基薄层细胞技术制片,根据《子宫颈细胞学Bethesda报告系统》(TBS)诊断系统做出诊断,并对结果进行回顾性分析。结果:12 672例宫颈标本中,发现鳞癌13例,占0.103%;腺癌3例,占0.024%;高度鳞状上皮内病变(HSIL)64例,占0.505%;低度鳞状上皮内病变(LSIL)146例,占1.152%,其中伴人乳头瘤病毒(HPV)感染90例,占0.710%;非典型鳞状细胞(ASC)651例,占5.137%;非典型腺细胞(AGUS)107例,占0.844%;未见上皮内病变细胞或恶性细胞(NILM)11 688例,占92.235%。结论:TCT和TBS系统能全面准确地反映宫颈病变的情况。早期发现癌前病变、早期治疗,阻止病变升级是防治宫颈癌的关键。
Objective: To investigate the incidence of cervical cancer and the significance of TCT in the diagnosis of gynecological diseases by using liquid-based thin-layer cell technique (TCT) on 12 672 cervical specimens. METHODS: 12 672 cervical specimens from January 2006 to February 2008 for cervical cytology were prepared using liquid-based lamellar techniques and diagnosed according to the “Cervical Bethesda Reporting System” (TBS) diagnostic system , And the results were retrospectively analyzed. Results: Among 12 672 cervical specimens, 13 cases were found squamous cell carcinoma (0.103%), 3 cases adenocarcinoma (0.024%), 64 cases (HSL) were 0.505%, and low grade squamous intraepithelial neoplasia There were 146 cases of LSIL (1.152%), of which 90 cases were associated with human papillomavirus (HPV) infection, accounting for 0.710%. There were 651 cases of atypical squamous cell carcinoma (ASC) accounting for 5.137% Cases, accounting for 0.844%; no epithelial lesions or malignant cells (NILM) 11 688 cases, accounting for 92.235%. Conclusion: TCT and TBS system can fully and accurately reflect the situation of cervical lesions. Early detection of precancerous lesions, early treatment, prevention of disease progression is the key to prevention and treatment of cervical cancer.