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采用随机对照的方法研究了中药（胃病冲剂）和小剂量三联疗法对慢性胃炎（ＣＧ）、消化性溃疡（ＰＵ）的疗效及幽门螺杆菌（Ｈｐ）清除和根除率，并进行了６～１８月随访的远期疗效观察，２０６例ＣＧ，９８例ＤＵ及９１例ＧＵ，均随机分为胃病冲剂、三联疗法及对照组；疗程四周。８１例ＰＵ获６～１８月随访结果Ｈｐ根除率：胃病冲剂组５３．８５％，三联组６９．８３％，显著高于对照组（Ｐ＜０．０１）。ＤＵ及ＧＵ愈合率：胃病冲剂组７９．３１％、６８．１８％；三联组８８．８９％、８１．８１％；对照组７２．０８％、６５．３０％。胃病冲剂及三联疗法根除Ｈｐ后溃疡复发率：６个月后根除者１２．５０％，未根除者５０．００％；１２月后根除者１０．５３％；１２月后根除者１０．５３％，未根除者为５５．００％（Ｐ＜０．０１）；１８月后根除者１／８例，未根除者５／１２例。冲剂组未发现副作用，三联组副作用少且轻微（８．９６％）。本组资料表明：胃病冲剂和三联疗法均为安全、有效的抗Ｈｐ治疗方法。
The curative effect of chronic gastritis (CG) and peptic ulcer (PU) and the elimination and eradication rate of Helicobacter pylori (Hp) were studied with randomized controlled study of traditional Chinese medicine (Weiwei Granule) and low dose triple therapy. Long-term efficacy of follow-up observation, 206 cases of CG, 98 cases of DU and 91 cases of GU, were randomly divided into stomach granules, triple therapy and control group; treatment of four weeks. Results 81 cases of PU were followed up for 6 to 18 months. Results Hp eradication rate was 53.85% in Weizhi granules group and 69.83% in triple group, which was significantly higher than that in control group (P <0.01). The healing rates of DU and GU were 79.31% and 68.18% in Weizhi granule group, 88.89% and 81.81% in triple therapy group and 72.08% and 65.30% in control group. Stomach disease granules and triple therapy to eradicate Hp ulcer recurrence rate: 6 months after eradication 12.50%, 50.0% of those who have not eradication; 12 months after eradication 10 53%; after December eradication 10.53% , 55.00% for those who were not eradication (P <0.01); 1/8 eradication and 5/12 cases of non-eradication after 18 months. Side effects were not found in the granule group, with few and minor side effects in the triple group (8.96%). This group of data shows that: stomach granules and triple therapy are safe and effective anti-Hp treatment.