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缺血性心血管疾病缺血性脑血管疾病和深静脉血栓栓塞的主要病理过程是血栓形成。在缺血性心脑血管疾病病理状态下,多种凝血因子增加,抗凝物质减少,纤溶活性降低。近年来研究表明,纤溶活性的下降是导致血栓形成的主要原因之一。预防血栓形成及溶解已形成的血栓是防治血栓栓塞性疾病的重要手段。随着人们对血栓栓塞性疾病病理机制及体内纤维蛋白溶解机制的进一步了解,抗栓溶栓药物的研究越来越多,现将近年来新
Ischemic cardiovascular disease The main pathological process of ischemic cerebrovascular disease and deep venous thromboembolism is thrombosis. In ischemic cardiovascular and cerebrovascular disease pathological conditions, a variety of coagulation factors increased anticoagulant substances decreased fibrinolytic activity decreased. In recent years, studies have shown that decreased fibrinolytic activity is one of the main causes of thrombosis. Prevention of thrombosis and the formation of thrombolysis has been an important means of prevention and treatment of thromboembolic diseases. With the further understanding of the pathological mechanism of thromboembolic diseases and the mechanism of fibrinolysis in vivo, there are more and more studies on antithrombotic drugs. In recent years, new