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应用多普勒超声法测定拉萨市(海拔3658m)15名健康男性世居藏族和11名健康男性移居汉族的颈内动脉平均血流速度,以了解高原居民运动时颈内动脉血流速度、脑血流量和脑氧供量的状况。两组的年龄、身高、体重、静息动脉血压和血红蛋白浓度相同。结果表明:静息时两组的颈内动脉的血流速度、脑血流量及脑氧供应量相似;次极量运动时,两组的血流速度和脑氧供量均增加;但在最大运动负荷时,仅藏族组的血流速度及脑氧供量增加。血流速度的增加可代偿最大运动时血氧饱和度降低所致的脑氧供量的下降。藏族组最大运动时脑氧供高于汉族组主要与脑血流量增加同时与血氧饱和度稍高有关,脑氧供增加可能提高最大运动负荷能力。
The average blood flow velocity of the internal carotid arteries of 15 healthy male living Tibetans and 11 healthy men migrating to Han nationality in Lhasa (altitude 3658m) was measured by Doppler echocardiography to understand the relationship between the blood flow velocity of internal carotid artery Blood flow and cerebral oxygen supply status. The two groups had the same age, height, weight, resting arterial blood pressure, and hemoglobin concentration. The results showed that the blood flow velocity, cerebral blood flow and cerebral oxygen supply of the internal carotid arteries of the two groups at rest were similar. In submaximal exercise, blood flow velocity and cerebral oxygen supply increased in both groups. However, At exercise load, blood flow and cerebral oxygen supply increased only in the Tibetan group. Increased blood flow compensates for a decrease in cerebral oxygen supply due to a decrease in blood oxygen saturation at maximal exercise. In the Tibetan group, the maximum cerebral oxygen supply was higher than that in the Han group mainly due to the increase of cerebral blood flow and slightly higher oxygen saturation. The increase of cerebral oxygen supply may increase the maximum exercise load capacity.