目的 急诊胆结石患者应用人性化护理服务，分析其对患者心理状态及疼痛变化改善情况。方法 选取60例2017年9月至2019年9月在我院急诊室接受治疗的胆结石患者，依据住院就诊时间进行分组，30例先入院治疗的患者为对照组，30例后入院治疗的患者为观察组，两组分别行常规护理和人性化护理措施，对比两组患者的心理状态和疼痛改善情况，并对两组的生活质量、手术相关指标、依从性、满意度及并发症进行对比分析。结果 ①施护前两组焦虑评分、抑郁评分无显著差异（P＞0.05）；施护后，观察组焦虑评分、抑郁评分均低于施护前及对照组“,”Objective To analyze the improvement of mental state and pain of patients with emergency gallstone by using humanized nursing service. Methods A total of 60 cases of cholelithiasis treated in the emergency room of our hospital from September 2017 to September 2019 were selected for analysis. They were divided into two groups according to the time of hospitalization， 30 patients who were hospitalized first were the control group， 30 patients who were hospitalized later were the observation group. The two groups were given routine nursing and humanized nursing measures respectively. The psychological state and pain changes of the two groups were compared and analyzed. The quality of life， operation related indexes， compliance， satisfaction and complications of the two groups were compared and analyzed. Results (1) There was no significant difference in anxiety score and depression score between the two groups before nursing (P ＞0.05); after nursing， the anxiety score and depression score of the observation group were lower than those before nursing and the control group (P ＜0.05). (2) In terms of pain score， there was no significant difference between the two groups before nursing (P ＞0.05); after nursing， the VAS score of the observation group was lower than that before nursing and the control group (P ＜0.05). In terms of pain degree， the moderate and severe pain in the observation group was significantly lower than that in the control group， and there were more painless patients than that in the control group (P ＜0.05). (3) In terms of quality of life， there was no significant difference in the scores of each dimension of GIQLI scale between the two groups before nursing (P ＞0.05); after nursing， the scores of conscious symptoms， psychological and emotional status， physical and physiological function and daily life in the observation group were higher than those in the control group (P ＜0.05). (4) In terms of postoperative recovery， the exhaust time， initial eating time， out of bed activity time and hospital stay in the observation group were shorter than those in the control group (P ＜0.05). (5) Before nursing， there was no significant difference in the scores of compliance and nursing satisfaction between the two groups (P ＞0.05); after nursing， the nursing compliance and nursing satisfaction of the observation group were higher than those of the control group (P ＜0.05). (6) In terms of complications， the probability of incision infection， biliary fistula， venous thrombosis and constipation in the observation group was significantly lower than that in the control group (P ＜0.05).Conclusion Application of humanized nursing service in the nursing of patients with emergency gallstone is more effective. It can help patients to improve their bad psychological state as soon as possible， reduce the degree of postoperative pain， enhance their compliance， reduce the patient\'s hospitalization time and complications， improve the treatment effect of patients， and finally make the patients recover to health as soon as possible.