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疱疹性皮炎是一种病因不明的丘疹一疱疹性皮肤病,常合并谷胶性肠道疾病,其发病机理既有遗传因素,又有免疫因素。病理变化除皮肤外,多数病人近端胃肠道有片状萎缩性粘膜损害,包括萎缩性胃炎,50%的病人可有胃肠道吸收功能试验异常。由于上胃肠道的病理改变以及胃酸缺乏,疱疹性皮炎病人对铁、维生素B_(12)以及叶酸的吸收功能都可能受损。这些病人缺铁的发生率为10~20%,有实验证明缺铁确是由于对食物铁吸收功能不良所致,但程度很轻。维生素B_(12)
Herpes dermatitis is a papulopathic dermatosis of unknown etiology, often associated with gluteal gut disease, the pathogenesis of both genetic and immune factors. Pathological changes In addition to the skin, the majority of patients with proximal gastrointestinal tract atrophic mucosal damage, including atrophic gastritis, 50% of patients may have abnormal gastrointestinal absorption test. Due to the pathological changes of the upper gastrointestinal tract and the lack of achlorhydria, the absorption of iron, vitamin B 12, and folic acid may be impaired in patients with herpetic dermatitis. The incidence of iron deficiency in these patients is 10 to 20%. Experiments have shown that iron deficiency is indeed due to poor absorption of iron in food, but to a lesser extent. Vitamin B_ (12)