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淋巴细胞中的K细胞在甲状腺疾病中其活力显著增高,在特异抗体存在时对靶细胞具有杀伤能力,导致甲状腺滤泡的破坏。近年来用~(51)Cr释放试验检测K细胞活力,受到重视。我们用此法对甲亢37例,桥本氏甲状腺炎14例,甲减3例,桥本甲亢4例,亚甲炎5例,甲状腺结节2例进行了检查。结果表明,除了甲状腺结节的~(51)Cr释放率低于对照组的正常值外,其余各组诸如甲亢、慢性淋巴性甲状腺炎、甲减、桥本甲亢、亚甲炎均显著高于正常值。这说明K细胞在大多数甲状腺疾患中起着免疫杀伤的作用。
K cells in lymphocytes have a markedly increased viability in thyroid diseases, killing target cells in the presence of specific antibodies, resulting in the destruction of thyroid follicles. In recent years ~ (51) Cr release test K cell activity, attention. We use this method in 37 cases of hyperthyroidism, Hashimoto’s thyroiditis in 14 cases, hypothyroidism in 3 cases, Hashimoto’s hyperthyroidism in 4 cases, 5 cases of methylene blue, thyroid nodules in 2 cases were examined. The results showed that, in addition to the thyroid nodule release rate of 51 (51) Cr lower than the normal control group, the remaining groups such as hyperthyroidism, chronic lymphocytic thyroiditis, hypothyroidism, Hashimoto’s Hyperthyroidism, methylene blue were significantly higher Normal value. This shows that K cells play an immunocidal role in most thyroid disorders.