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目的:研究雌激素受体β在子宫内膜以及子宫内膜异位灶中的表达。方法:用反转录聚合酶链式扩增以及免疫组化法测定在位及异位子宫内膜组织中雌激素受体βmRNA以及蛋白的表达。结果:在位及异位子宫内膜都探测到雌激素受体βmRNA,而在位及异位内膜用免疫组化法均未探测到雌激素受体β蛋白。结论:在位及异位子宫内膜组织不表达雌激素受体β蛋白。
Objective: To study the expression of estrogen receptor β in endometrium and endometriosis. Methods: The expression of estrogen receptor β mRNA and protein in eutopic and ectopic endometrium was detected by reverse transcriptase polymerase chain reaction and immunohistochemistry. Results: Estrogen receptor β mRNA was detected in eutopic and ectopic endometrium, while estrogen receptor β protein was not detected in eutopic and ectopic endometrium by immunohistochemistry. Conclusion: Eutopic and ectopic endometrial tissues do not express estrogen receptor beta protein.