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目的:探讨妊娠女性体内铁含量对孕妇不宁腿综合征发病的影响。方法:检测门诊孕期28周以上症状性不宁腿综合征孕妇、正常孕妇及健康女性体内血清铁、血清铁蛋白、血清可溶性转铁蛋白受体含量,并对检测结果做统计学分析。结果:血清铁、血清铁蛋白、血清可溶性转铁蛋白受体含量在症状性不宁腿综合征孕妇分别为(16.7±2.6)μmol/L、(29.3±3.2)μg/L和(38.2±8.5)nmol/L,在正常孕妇分别为(17.1±3.0)μmol/L、(30.2±4.4)μg/L和(36.0±6.3)nmol/L,在健康女性分别为(18.5±4.0)μmol/L、(36.8±5.9)μg/L和(27.9±4.3)nmol/L。症状性不宁腿综合征孕妇与健康女性在血清铁蛋白、血清可溶性转铁蛋白受体含量之间差异有统计学意义(P<0.01);不宁腿综合征孕妇与正常孕妇各检测指标之间差异无统计学意义。结论:妊娠女性体内铁缺乏可能是诱发孕妇发生不宁腿综合征的重要因素。
Objective: To investigate the effect of iron content in pregnant women on the incidence of restless legs syndrome in pregnant women. Methods: The levels of serum iron, serum ferritin and serum soluble transferrin receptor in pregnant women with normal restless legs syndrome, pregnant women with normal rest and healthy women over 28 weeks pregnant during outpatient pregnancy were detected, and the results were analyzed statistically. Results: The contents of serum iron, serum ferritin and serum soluble transferrin receptor were (16.7 ± 2.6) μmol / L, (29.3 ± 3.2) μg / L and (38.2 ± 8.5) ) nmol / L were (17.1 ± 3.0) μmol / L, (30.2 ± 4.4) μg / L and (36.0 ± 6.3) nmol / L respectively in normal pregnant women and 18.5 ± 4.0 μmol / L , (36.8 ± 5.9) μg / L and (27.9 ± 4.3) nmol / L, respectively. Symptomatic restless legs syndrome pregnant women and healthy women in serum ferritin, serum soluble transferrin receptor content was significantly different (P <0.01); Restless legs syndrome pregnant women and normal pregnant women, the detection of indicators There was no significant difference between the two groups. Conclusion: Iron deficiency in pregnant women may be an important factor in inducing restless legs syndrome in pregnant women.