论文部分内容阅读
目的探讨不同时机介入微弹簧圈栓塞治疗对脑动脉瘤破裂患者近期预后的影响,为临床治疗提供参考依据。方法回顾性分析78例脑动脉瘤破裂患者的一般资料,根据不同治疗时间分为早期组46例和晚期组32例,早期组入院72 h内行微弹簧圈栓塞治疗,晚期组入院72 h后行微弹簧圈栓塞治疗,比较2组临床疗效及并发症发生率,随访6个月后比较2组改良日常生活能力(MBI)、改良Rankin量表(mRS)评分及复发情况。结果早期组完全栓塞、次全栓塞、不完全栓塞率均优于晚期组(P均<0.05);术后6个月,早期组MBI、mRS评分均优于晚期组(P<0.05);早期组脑积水、动脉瘤再次破裂、蛛网膜下腔出血发生率及复发率均低于晚期组(P<0.05)。结论早期介入微弹簧圈栓塞治疗提高了脑动脉瘤破裂患者的临床疗效,改善了患者近期神经功能和日常生活能力,且降低了并发症发生率和复发率,值得临床重视。
Objective To investigate the effect of embolization with different coils on the short-term prognosis of patients with aneurysm rupture and to provide reference for clinical treatment. Methods A retrospective analysis of 78 cases of cerebral aneurysm rupture in patients with general information, divided into early treatment group according to different treatment time 46 cases and 32 cases of advanced group, the early group within 72 h after embolization with coil spring embolization group 72h after admission Micro-coil embolization was used to compare the clinical efficacy and incidence of complications in both groups. After 6 months follow-up, MBI, mRS score and recurrence were compared between the two groups. Results The rate of complete embolization, subembolization and incomplete embolization in early stage group were better than those in advanced stage group (all P <0.05). At 6 months after operation, MBI and mRS score in early stage group were better than those in advanced stage group (P <0.05) Hydrocephalus group, aneurysm rupture again, the incidence of subarachnoid hemorrhage and recurrence rate were lower than the late group (P <0.05). Conclusion Early interventional micro-coil embolization improves the clinical curative effect of patients with ruptured cerebral aneurysms, improves the patients’ recent neurological function and daily living ability, and reduces the complication rate and recurrence rate, which deserves clinical attention.