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青年人患有胰岛素依赖性糖尿病两倍于其它内分泌紊乱疾病。替代疗法虽然已应用了60多年,但 仍然不十分满意。目前,认为预防,延缓或恢复微血管并发症的关键是维持24小时血糖水平正常,达到数年如一日。采用注射泵或多次注射胰岛素的新替代疗法,对少数几组经过选择的患者是有效的,不会出现明显的低血糖和威胁生命,但是对于一些不能或不允许使用这种强化方法的患者,只能采取移植全胰或仅仅移植郎格罕氏岛的方法以代替产生胰岛素的细胞。
Young people suffer from insulin-dependent diabetes twice as often as other endocrine disorders. Although more than 60 years of replacement therapy has been used, it is still not very satisfactory. At present, the key to preventing, delaying or restoring microvascular complications is to maintain a normal 24-hour blood glucose level for several years, such as one day. New alternative therapies using a syringe pump or multiple injections of insulin are effective for a small group of selected patients without significant hypoglycaemia and life threatening but for patients who can not or will not allow the use of such fortification , Only the method of transplanting whole pancreas or only transplantation of Langerhans Island can be used instead of insulin-producing cells.