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在肾上腺髓质(BAM)中有许多含有一个或几个脑啡肽片段的多肽,如多肽I、B、F及BAM-12P,-20P,-22P等。作者最近又从牛肾上腺髓质中分得一个新的多肽-多肽E,经氨基酸顺序分析表明,它有25个氨基酸组成,分子量为3200道尔顿,羧C-末端有亮-脑啡肽片段,氨基N-末端有甲硫-脑啡肽片段(图略),与多肽I比较,多肽E显然是多肽I的15～39的片段。经豚鼠回肠和NG-108杂交细胞阿片受体结合试
There are many polypeptides in the adrenal medulla (BAM) that contain one or more enkephalin fragments, such as polypeptides I, B, F and BAM-12P, -20P, -22P and the like. Recently, the authors also obtained a new peptide, polypeptide E, from the bovine adrenal medulla. The amino acid sequence analysis showed that it has 25 amino acids with a molecular weight of 3200 Daltons and a bright enkephalin fragment , N-terminal methionine - enkephalin fragment (Figure omitted), compared with the polypeptide I, polypeptide E is clearly a polypeptide I fragment 15 ~ 39. The guinea pig ileum and NG-108 hybrid cells opioid receptor binding assay