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患女,45岁,因风湿性关节炎予以抗风湿治疗.为加强疗效而进行免疫增强治疗.服左旋咪唑100mg,服后4h 出现发冷、寒战、发烧伴四肢肌肉酸痛,皮肤痛觉过敏,乏力而卧床不起.查体:T39.6℃,无皮疹,全身淋巴结不肿大,咽无红肿,心、肺正常,肝、脾未触及,发烧考虑为左旋咪唑引起的药物热.未治疗,观察24h 后体温降至正常.1周后再次服用左旋咪唑100mg,服后5h,再次出现发烧39.0℃及上述症状,仍未治疗,15h 后,体温自行降至正常.其它症状消失.
Female, 45 years old, due to rheumatoid arthritis to be treated with anti-rheumatoid.In order to enhance the efficacy of immune enhancement therapy.Of levamisole 100mg, 4h after service, chills, chills, fever with limb muscle soreness, skin hyperalgesia, fatigue And bedridden. Examination: T39.6 ℃, no rash, systemic lymphadenopathy is not swollen, pharyngeal no swelling, heart, lungs normal, liver, spleen not touched, fever considered as levamisole caused by drug fever .Unreated, After 24 hours, the body temperature dropped to normal. After 1 week, levamisole 100 mg was taken again, and 5 hours after taking the medicine, fever 39.0 ° C and the above symptoms appeared again. After 15 hours, the body temperature went down to normal. Other symptoms disappeared.