从1981年至1985年8月共作外周血淋巴细胞及羊水细胞G带染色体检查1155人次,发现异常核型62例,其中4例属世界首报。4例中,3例为染色体相互平衡易位携带者,皆有不良妊娠史,1例患原发闭经,有X染色体短臂重复。 From 1981 to August 1985 a total of 1155 peripheral blood lymphocytes and amniotic fluid cell G chromosome examination revealed abnormal karyotype in 62 cases, of which 4 cases are the world’s first reported. Of the 4 cases, 3 were carriers of balanced chromosomal translocations, both had a history of adverse pregnancy, 1 had primary amenorrhea, and had a short arm repeat of the X chromosome.