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研究了杯［６］芳烃－双金属卟啉仿Ｐ４５０酶模型化合物对环己烯环氧化反应的催化性能．考察了温度、氧源浓度、催化剂浓度、底物浓度、卟啉环中位苯基上取代基、溶剂等因素对反应的影响．结果表明，杯［６］芳烃－双金属卟啉的催化性能优于相应的简单金属卟啉单体，且反应遵从Ｍｉｃｈａｅｌｉｓ－Ｍｅｎｔｅｎ规律．这是由于作为疏水结合部位的杯［６］芳烃大环的引入，导致多部位识别协同催化，从而极大地提高了金属卟啉的催化性能．
The catalytic properties of calix [6] arene-bimetallic porphyrin P450 enzyme model for the epoxidation of cyclohexene were studied. The influences of temperature, concentration of oxygen source, concentration of catalyst, substrate concentration, phenyl substituent on the phenyl group in the porphyrin ring and solvent were investigated. The results showed that the catalytic properties of calix [6] arene-bimetallic porphyrin is better than that of the corresponding simple metalloporphyrin monomer and the reaction follows the Michaelis-Menten law. This is due to the introduction of the cup [6] arene macrocycle as a hydrophobic binding site, resulting in synergistic catalysis of multi-site recognition, thereby greatly improving the catalytic properties of metalloporphyrins.