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风湿性疾患常有白细胞减少。为研究风湿病的粒细胞贮存状况,采用还原尿睾酮(etiocholanolone)试验法观察了一组不同类型的风湿病患者。该组病人共18人,男3例,女15例,年龄27-60岁,其中类风湿性关节炎10例,Felty(?)综合症2例、红斑狼疮3例、Sharp(?)综合症、SudecK(?)病和牛皮癣性关节炎各1例。16名健康男女作为对照。两组受试者均肌注1%还原尿睾酮丙乙醇溶液(0.1mg/kg),用药前一天下午3时和用药后15小时作周围血粒细胞计数及分类计数,并求出用药后15小时的粒细胞数和正常最低数之间的差异(ΔG),统计各例的均数和标准差(SD)以及粒细胞最低数的变化系数(CV)。
Rheumatic diseases often have leukopenia. In order to study the storage of granulocytes in rheumatoid arthritis, a group of different types of rheumatic patients were observed using the etiocholanolone test. The group of 18 patients, 3 males and 15 females, aged 27-60 years, of which 10 cases of rheumatoid arthritis, Felty (?) Syndrome in 2 cases, 3 cases of lupus erythematosus, Sharp (?) Syndrome , SudecK (?) And psoriatic arthritis in 1 case. 16 healthy men and women as a control. Two groups of subjects were intramuscular 1% reduction of urinary testosterone propanol solution (0.1mg / kg), the day before medication at 3 pm and 15 hours after treatment for peripheral blood granulocyte count and classification of the count and found after treatment 15 The difference between the number of granulocytes and the normal minimum (ΔG), the mean and standard deviation (SD) of each case, and the coefficient of variation (CV) of the lowest number of granulocytes were calculated.