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50%以上的骨髓瘤(MM)患者出现肾衰竭且常因此死亡。典型的骨髓瘤肾,明确诊断需做肾活检。最近作者等由尿中检查出骨髓瘤管型,对骨髓瘤肾的出现与否有鉴别意义。共观察30例MM患者(分型IgG14,IgA5 K链7,λ链3,非分泌1)取清晨或午间自然排出的尿液,同时做常规及各项化学检查,并取10ml混匀尿液490g离心10分钟,留沉淀物0.5ml,加0.5ml生理盐水再混匀,对各种细胞成份计数;另取此标本250μl用细胞离心器处理,沉渣于Saccomenno液
Renal failure occurs in more than 50% of myeloma (MM) patients and often leads to death. The typical diagnosis of myeloma kidneys requires a renal biopsy. Recently, the authors have examined the myeloma casts in the urine and have differentiated the presence or absence of myeloma kidneys. A total of 30 MM patients (typed IgG14, IgA5 K-chain 7, λ-chain 3, non-secretory 1) were taken for urine naturally excreted in the early morning or midday, while routine and various chemical tests were performed, and 10 ml of urine was mixed. Centrifuge at 490g for 10 minutes, leave 0.5ml sediment, add 0.5ml physiological saline and mix well, count various cell components; take another 250μl of this sample and treat it with a cell spinner, sediment in Saccomenno solution