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[目的]探讨口服胃窗声学造影剂超声对胃部疾病疾病的诊断价值。[方法]入选经病理诊断确诊的108例胃部疾病患者作为观察组,均接受胃区常规超声、口服胃窗声学造影剂超声和胃镜检查;另选择同期经体检示无胃部疾病的健康志愿者33例作为对照组。对比观察2组超声表现和胃壁厚度,以病理诊断为金标准,观察常规超声、超声造影诊断胃部疾病的准确率。[结果]对照组胃壁超声图像呈清晰的5层结构,回声表现为3层强回声夹着2层弱回声,胃蠕动正常,胃壁连续完整,无增厚;观察组胃壁病变处出现不同程度增厚,局部胃壁蠕动减弱或消失,部分胃壁层次结构不清,并向周围邻近处浸润或转移;与对照组相比,观察组患者的胃病变处胃壁厚度显著增加(P<0.05);同时在良、恶性病灶的胃壁厚度对照中发现,恶性病灶的胃壁厚度明显大于良性病灶的胃壁厚度(P<0.05),超声造影诊断准确率显著高于胃常规超声(χ~2=34.012,P<0.05)。[结论]与胃常规超声相比,口服胃窗声学造影剂超声可以显著提高胃部疾病的诊断准确率,且操作简单,安全无痛苦,值得临床积极借鉴。
[Objective] To investigate the diagnostic value of oral gastric window contrast agent ultrasound in the diagnosis of gastric diseases. [Methods] One hundred and eighty patients with gastric diseases diagnosed by pathological examination were selected as the observation group. All patients underwent gastric ultrasound and gastroscopy under oral ultrasound and gastroscopy. Another healthy volunteer who did not have gastric diseases during the same period 33 cases as control group. Comparing the two groups of ultrasound findings and gastric wall thickness, with the pathological diagnosis as the gold standard, observe the conventional ultrasound, contrast-enhanced ultrasound in the diagnosis of gastric disease accuracy. [Results] In the control group, the gastric wall ultrasound image showed a clear five-layer structure. The echogenicity was characterized by three layers of strong echo with two layers of weak echo, normal gastric motility, continuous and complete gastric wall without thickening, The local gastric wall motility was weakened or disappeared, some of the gastric wall was unclear in structure and infiltrated or moved into the surrounding area. Compared with the control group, the gastric wall thickness in the gastric lesion was significantly increased in the observation group (P <0.05) The gastric wall thickness in benign and malignant lesions was found to be significantly larger than that in benign lesions (P <0.05). The diagnostic accuracy of CEUS was significantly higher than that of conventional gastric ultrasound (χ ~ 2 = 34.012, P <0.05) ). [Conclusion] Compared with conventional gastric ultrasound, oral gastric window ultrasound contrast agent can significantly improve the diagnostic accuracy of gastric diseases, and the operation is simple, safe and painless, it is worth actively clinical reference.