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目的:了解布鲁氏杆菌检出率与布病患者急慢性期及是否应用抗菌素有直接的关系,为制定相应的防治措施提供依据。方法:采用虎红平板凝集试验(RBPT)初筛,试管凝集试验(SAT)确诊,血培养(双向培养基培养)进行细菌学检验[1]。结果:在未考虑是否使用抗菌素前提下布鲁氏杆菌检出率在急性期和慢性期上差别无统计学意义(p>0.05),布鲁氏杆菌检出率在急性期,用抗菌素与未用抗菌素上差别有统计学意义(p<0.05),布鲁氏杆菌检出率在慢性期,用抗菌素与未用抗菌素上差别统计学意义(p<0.05)。结论:布鲁氏菌病患者血液中布鲁氏杆菌检出率高低与是否应用抗菌素由着直接的关系。因此为提高布鲁氏杆菌检出率不论是在急性期还是在慢性期都应尽量在未使用抗菌素之前培养。
Objective: To understand the detection rate of brucellosis in patients with brucellosis and whether the application of antibiotics has a direct relationship, to provide the basis for the prevention and treatment measures. Methods: The RBPT screening, the coagulation test (SAT) test and the blood culture (two-way culture medium) were used for bacteriological examination [1]. Results: There was no significant difference in the detection rate of Brucella between the acute phase and the chronic phase without considering the use of antibiotics (p> 0.05). The detection rate of brucella was in acute phase, The difference was statistically significant with antibiotics (p <0.05). The detection rate of brucellosis was in the chronic phase, with statistically significant difference between antibiotics and unused antibiotics (p <0.05). Conclusion: The detection rate of brucellosis in the blood of brucellosis patients is directly related to the use of antibiotics. Therefore, to improve the detection rate of brucellosis in both acute and chronic phase should try not to use antibiotics before training.