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目的:探讨复方氯己定含漱液对口腔溃疡的临床治疗效果。方法:选取448例口腔溃疡患者进行分析,随机将其分为对照组(224例)和观察组(224例),对照组患者采取外用喷涂西瓜霜喷雾剂,观察组患者采取复方氯已定溶液漱口,并比较两组患者临床治疗效果、口腔清洁情况以及不良反应发生率。结果:与对照组比较,观察组患者其临床治疗总有效率显著提高,两者间比较差异具有统计学意义(P<0.05);观察组患者其口腔清洁情况显著优于对照组,两者间比较差异显著具有统计学意义(P<0.05);观察组恶心呕吐1例、皮疹1例,对照组恶心呕吐2例、皮疹1例,两组患者不良反应发生率比较差异无统计学意义(P>0.05)。结论:复方氯已定含漱液对口腔溃疡疾病具有显著治疗效果,且不良反应轻微,该方法值得推广应用。
Objective: To investigate the clinical effect of compound chlorhexidine gargle on oral ulcer. Methods: Forty-eight patients with oral ulcer were selected and randomly divided into control group (224 cases) and observation group (224 cases). Patients in control group were treated with topical watermelon cream spray. Patients in observation group were treated with compound chloridazine solution Gargle, and compared the clinical efficacy of two groups of patients, oral hygiene and adverse reactions. Results: Compared with the control group, the total effective rate of clinical observation in the observation group was significantly increased (P <0.05), and the oral hygiene in the observation group was significantly better than that of the control group (P <0.05). The observation group had nausea and vomiting in 1 case, skin rash in 1 case, control group with nausea and vomiting in 2 cases and skin rash in 1 case. There was no significant difference in adverse reaction between the two groups (P > 0.05). Conclusion: The compound chlorhexidine gargle has a significant therapeutic effect on oral ulcer disease with mild adverse reactions. This method is worthy of wide application.