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目的探讨腹腔镜和开腹胆囊切除术手术对急性结石性胆囊炎患者临床疗效和IL-6的影响。方法回顾性分析40例腹腔镜胆囊切除术(LC)与40例开腹胆囊切除术(OC)患者的临床资料,对比两组患者手术时间、下床活动时间、术后肛门排气时间、住院时间、术中出血量、术前后白介素-6(IL-6)水平变化。结果 LC组手术时间、下床活动时间、术后肛门排气时间、住院时间均较OC组短,术中出血量也少于OC组,与OC组比较差异有统计学意义(P<0.05);术后OC组IL-6水平明显高于LC组,两组比较差异有统计学意义(P<0.05)。结论 LC治疗急性胆囊炎可以明显改善临床疗效和炎症因子水平,是一种安全可行的手术方式。
Objective To investigate the effect of laparoscopic and open cholecystectomy on clinical efficacy and IL-6 in patients with acute calcific cholecystitis. Methods The clinical data of 40 patients with laparoscopic cholecystectomy (LC) and 40 patients with open cholecystectomy (OC) were retrospectively analyzed. The operative time, ambulation time, postoperative anal exhaust time, hospitalization Time, intraoperative blood loss, preoperative and postoperative IL-6 levels change. Results The operation time, time of ambulation, time of postoperative anal exhaust and hospital stay in LC group were shorter than those in OC group, and the amount of bleeding during operation was less than that in OC group. There was significant difference between OC group and OC group (P <0.05) The level of IL-6 in OC group was significantly higher than that in LC group (P <0.05). Conclusion LC treatment of acute cholecystitis can significantly improve the clinical efficacy and levels of inflammatory cytokines, is a safe and feasible surgical approach.