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为评价气管内置管注药治疗局限性异物性支气管肉芽肿的临床疗效 ,对 2 6例局限性异物性支气管肉芽肿患者在纤维支气管镜 (纤支镜 )介入下气管内留置 6F导管 ,每日经导管分 2次注入 2 %利多卡因 5ml+无菌生理盐水 10ml+地塞米松 5mg +抗生素 (阿米卡星 0 2g或头孢三嗪 1 0g) ,治愈 2 5例 ,手术 1例 ,治愈率 96 2 % ,疗程 6～ 15天。 2 9例按常规静脉抗炎治疗加雾化吸入或隔日纤支镜下注药治疗 ,治愈 2 4例 ,手术 5例 ,治愈率 82 8% ,疗程 6～32天。结果表明 ,气管内置管注药治疗局限性异物性支气管肉芽肿 ,具有局部抗炎效果好、减少静脉应用抗生素剂量和毒副作用、缩短病程以及患者能够耐受等优点 ,有望临床推广应用
To assess the clinical efficacy of endotracheal intubation for the treatment of localized foreign body bronchial granuloma, 6F catheters were placed in the trachea on 26 patients with localized foreign body bronchogenic granuloma under daily bronchoscopy (bronchofibroscopy) The catheter was divided into 2 times 2% lidocaine 5ml + sterile saline 10ml + dexamethasone 5mg + antibiotics (amikacin 0 2g or ceftriaxone 10g), cured 25 cases, 1 case of surgery, the cure rate 96 2%, course of treatment 6 to 15 days. 29 cases were treated by conventional intravenous anti-inflammatory plus nebulized inhalation or every other day under bronchoscopy, 24 cases were cured and 5 cases were cured. The cure rate was 82.8%. The course of treatment was 6 to 32 days. The results showed that intratracheal instillation of drug injection for the treatment of localized foreign body bronchial granuloma with local anti-inflammatory effect, reducing the dose of intravenous antibiotics and side effects, shorten the duration and patient tolerance, etc., is expected to promote the clinical application