围绝经期是指内分泌紊乱已经开始,大多表现为月经周期不规则。由于卵泡的持续存在、雌激素合成增多,而引起月经周期延长及突破性出血,但有时出现典型的更年期症状,如:潮热、多汗、失眠、疲乏及情绪抑制等。围绝经期综合征与卵巢功能衰退之间有因果关系,因绝经过渡期的雌二醇(E2 Perimenopausal period refers to the endocrine disorder has begun, most of the performance of irregular menstrual cycles. As the follicles persist, estrogen synthesis increased, causing the menstrual cycle and breakthrough bleeding, but sometimes typical symptoms of menopause, such as: hot flashes, hyperhidrosis, insomnia, fatigue and depression and so on. There is a causal relationship between perimenopausal syndrome and ovarian dysfunction, due to menopausal transitional estradiol (E2