异烟肼作为“一线”抗痨药临床应用广泛,其毒副反应以往有诸多报道,但其致呼吸停止者罕见。现将所见1例报道如下: 临床资料患者,男,4个月。因发热、咳嗽4天于1989年6月2日入院。有结核接触史、入院查T38.7℃,R30次/分。颈软,双肺呼吸音粗未闻及干湿性罗音。HR146次/分,律齐,无杂音。腹(一)。实验室检查:血WBC20×10~9/L,N76%,L24%。ESR 50mm/1小时。胸片:两侧肺门阴影增大,边缘模糊。右肺门有肿大淋巴结阴影,OT试验:硬结直径>20mm。既往无卡介苗接种史。入院诊断肺门结核。于1989年6月13日9点30分给 Isoniazid as a “first-line” anti-tuberculosis clinical application of a wide range of its adverse reactions in the past there are many reports, but it caused a rare stop breathing. Now we see a case reported as follows: Clinical data patients, male, 4 months. Due to fever, cough for 4 days in June 2, 1989 admission. A history of contact with tuberculosis, admitted to check T38.7 ℃, R30 times / min. Soft neck, lung breath sounds unremarkable and wet and dry rales. HR146 times / min, law Qi, no noise. Abdomen (a). Laboratory tests: blood WBC20 × 10 ~ 9 / L, N76%, L24%. ESR 50mm / 1 hour. Chest radiograph: hilar shadow on both sides increases, blurred edges. Right hilar lymph nodes have swollen shadow, OT test: induration diameter> 20mm. No past history of BCG vaccination. Admission diagnosis of hilar tuberculosis. At 9:30 on June 13, 1989 to give