无脑畸胎发病机理有争论:一种认为露脑畸形作为最初缺陷可能或不能发展成无脑畸形。第二种认为胎儿颅骨缺乏或不完全作为主要的病理机理会导致发展成无脑畸形。第三种是软的脑组织没有足够的骨板保护,暴露于机械或化学的损伤,如大脑半球受损伤可以导致部分脑组织破坏。当组织广泛破坏时,最终的病理显示无脑畸形。用经阴道超声扫描能够早期诊断神经管缺陷和其他伴 No brain teratogenic pathogenesis controversial: a think deformity as the initial defect may or may not develop into anencephaly. The second is that lack or incomplete fetal skull as the main pathological mechanism will lead to the development of anencephaly. The third is that soft brain tissue does not have sufficient plate protection, exposure to mechanical or chemical damage, such as damage to the cerebral hemisphere can lead to partial brain tissue damage. When the tissue is extensively destroyed, the final pathology shows no brain abnormalities. Transvaginal sonography can early diagnose neural tube defects and other partners